• Users Online: 19141
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
RESEARCH ARTICLE
Year : 2019  |  Volume : 56  |  Issue : 4  |  Page : 295-302

Involvement of dual serotypes during a severe dengue outbreak in Wadi area, Nagpur district, Maharashtra 2017


1 ICMR–National Institute of Virology, Pune, Maharashtra, India
2 District Malaria Officer, Malaria Department, Nagpur Division, Nagpur, Maharashtra, India
3 District Medical Officer, Vyahad PHC, Wadi, Nagpur, Maharashtra, India
4 State Entomologist, Maharashtra, India

Correspondence Address:
Dr. A B Sudeep
ICMR–National Institute of Virology, Microbial Containment Complex, Sus Road, Pashan, Pune–411 021
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-9062.302031

Rights and Permissions

Background & objectives: An outbreak of dengue-like illness was reported from Wadi area within the Nagpur Municipal Corporation during September–October 2017 with five deaths. Major symptoms reported were high fever (103–106 oF), acute joint pains, myalgia, drowsiness, breathlessness, etc. An investigation was conducted to confirm the etiological agent, its characterization and the vectors involved in the outbreak. Methods: Serological analysis was conducted to detect dengue (DEN)/chikungunya IgM antibodies in 158 sera samples. Nested-PCR was carried out to serotype eight ELISA positive samples. Adult and larval mosquito collections were conducted in the affected areas to determine species composition and mosquito density. Results: Dengue IgM antibodies were detected in 44 sera samples. Molecular typing revealed involvement of DEN-2 and DEN-3 serotypes. Dengue hemorrhagic fever symptoms were observed in two patients. Aedes aegypti breeding was found rampant with Breteu index and house index ranging from 23 to 70 and 17 to 56, respectively. Major breeding habitats encountered were, used tyres, cement tanks and refrigerator trays. Interpretation & conclusion: Clinical symptoms, detection of anti-DEN IgM antibodies in high number of samples and heavy breeding of Ae. aegypti confirmed it was a dengue outbreak.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1920    
    Printed26    
    Emailed0    
    PDF Downloaded198    
    Comments [Add]    
    Cited by others 1    

Recommend this journal