• Users Online: 374
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
 
RESEARCH ARTICLE
Ahead of Print

Changing clinico-epidemiology of post-kala-azar dermal leishmaniasis (PKDL) in India: Results of a survey in four endemic states


1 Zonal Coordinator Neglected Tropical Diseases, WHO India, Muzaffarpur, India
2 State Coordinator Neglected Tropical Diseases, WHO India, Kolkata, India
3 State Coordinator Neglected Tropical Diseases, WHO India, Ranchi, India
4 Dr Zonal Coordinator Neglected Tropical Diseases, WHO India, Maldah, India
5 Zonal Coordinator Neglected Tropical Diseases, WHO India, Darjeeling, India
6 State Coordinator Neglected Tropical Diseases, WHO India, Patna, India
7 Zonal Coordinator Neglected Tropical Diseases, WHO India, Purnea, India
8 State Coordinator Neglected Tropical Diseases, WHO India, Raipur, India
9 Zonal Coordinator Neglected Tropical Diseases, WHO India, Dumka, India
10 Sub-regional Team Leader, WHO India, Muzaffarpur, Bihar, India
11 Zonal Coordinator Neglected Tropical Diseases, WHO India, Gorakhpur, India

Correspondence Address:
Suman Saurabh,
Zonal Coordinator Neglected Tropical Diseases, World Health Organization India, Muzaffarpur
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-9062.310875

Background & objectives: Detection and treatment of post-kala-azar dermal leishmaniasis (PKDL) cases is considered important for kala-azar elimination. The objective of our study was to find out the proportion of different forms of lesions, interruption of treatment and rate of treatment completion, cure rates of PKDL, risk factors for developing severe forms of PKDL and utilization of services offered by the kala-azar elimination program. Methods: A cross-sectional survey of PKDL patients registered for treatment at all levels of care during 2015 and 2016 was done. Results: 576 PKDL patients who had started treatment in 2015 and 2016 were studied. Three-fourths of all patients were found to be clinically cured after a year of follow-up. Around 90% lesions were of macular type. Interruption of treatment was observed in one-fourth of PKDL patients. Around 79% patients had past history of kala-azar treatment. Discontinuation of treatment during earlier kala-azar episode was significantly associated with the development of papular and nodular forms of lesion. 43% of patients had received the incentive of INR 2000 after completion of treatment. Around three-fourths women in the reproductive age group were found not to use any contraceptive method during PKDL treatment. Interpretation & conclusions: PKDL treatment interruption should be reduced through ensuring drug supply and timely retrieval of patients. Directly observed treatment should be implemented and combination regimen should be explored to improve final cure rate. Delivery of financial incentive to PKDL patients and counselling and contraception to women of reproductive age group should be improved.


Print this article
Search
 Back
 
  Search Pubmed for
 
    -  Saurabh S
    -  Roy P
    -  Pandey DK
    -  Ray D
    -  Tarak S
    -  Pandey R
    -  Kumar D
    -  Jamil S
    -  Paulraj A
    -  Kumar A
    -  Dutta S
 Citation Manager
 Article Access Statistics
 Reader Comments
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed151    
    PDF Downloaded0    

Recommend this journal