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Concomitant falciparum malaria and Hyperreactive Malarial Splenomegaly in an adolescent boy from eastern India: A tale of rare coincidences

1 Department of Tropical Medicine, School of Tropical Medicine, Kolkata, West Bengal, India
2 Department of Internal Medicine, King George Medical University, Shamina road, Lucknow, Uttar Pradesh, India

Correspondence Address:
Saurabh Pandey,
Department of Internal Medicine, King George Medical University, Shamina road, Lucknow
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-9062.311782

Hyperreactive malarial splenomegaly (HMS) is one of the important causes of massive splenomegaly in malaria endemic zone. It is thought to represent a dysfunctional immune response to recurrent malarial infection. It is usually reported due to physical symptoms of splenomegaly and hypersplenism and fever is classically absent. Concomitant malaria with HMS is a very rare finding in the Indian context. Here, we report a case of symptomatic falciparum malaria presented with fever, jaundice, massive splenomegaly and pancytopenia. Persistent massive splenomegaly led us to investigate thoroughly and finally diagnosed it as HMS with concomitant falciparum malaria. He received standard antimalarial treatment and 12 months of weekly chloroquine and completely recovered without any relapse or complications.

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