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  Indian J Med Microbiol
 

Figure 1: Nitric oxide level and malaria pathogenesis. Balb/c mice were infected with 5×105 Plasmodium berghei (Pb) parasitized erythrocytes via intraperitoneal injection (A) Serum was collected from infected mice and level of nitric oxide was determined. Infected mice were divided into 3 groups: Pb-infected, Pb-infected mice fed with L-arginine and another group consisted of infected mice fed with L-citrulline. Uninfected mice were used as control. Blood collected from tails was used to prepare smears to determine parasitic load (B) Survival of mice (C) Immunohistochemistry of spleen of Balb/c mice (Uninfected, infected and arginine fed and citruine fed mice (D). Black arrows indicate the parasitized RBC in spleen at 1000× original magnification. Data is shown as representative of four independent experiments consisting of three mice in each group

Figure 1: Nitric oxide level and malaria pathogenesis. Balb/c mice were infected with 5×10<sup>5</sup> <i>Plasmodium berghei</i> (Pb) parasitized erythrocytes via intraperitoneal injection (A) Serum was collected from infected mice and level of nitric oxide was determined. Infected mice were divided into 3 groups: Pb-infected, Pb-infected mice fed with L-arginine and another group consisted of infected mice fed with L-citrulline. Uninfected mice were used as control. Blood collected from tails was used to prepare smears to determine parasitic load (B) Survival of mice (C) Immunohistochemistry of spleen of Balb/c mice (Uninfected, infected and arginine fed and citruine fed mice (D). Black arrows indicate the parasitized RBC in spleen at 1000× original magnification. Data is shown as representative of four independent experiments consisting of three mice in each group